Bronchoscopic Lung Volume Reduction
نویسندگان
چکیده
Chronic obstructive pulmonary disease (COPD) is common and has significant morbidity mortality as the fourth leading cause of death in United States. In many patients, particularly those with emphysema, COPD characterized by markedly increased residual volume contributing to exertional dyspnea. Current therapies have limited efficacy. Surgical resection diseased areas lung reduce was effective identified subgroups but also had suboptimal cost effectiveness. Lung-volume reduction, using bronchoscopic techniques, shown substantial benefits a broader patient population less mortality. This review meant spread awareness about lung-volume reduction promote its consideration early referral for patients advanced emphysema frequently encountered both primary care physicians specialists. A search conducted on PubMed (MEDLINE), EMbase, Cochrane library original studies, following keywords: “lung-volume reduction.” “endobronchial valves,” “intrabronchial “bronchoscopic reduction,” “endoscopic We included reports from systematic reviews, narrative clinical trials, observational studies. Two reviewers evaluated potential references. total 27 references were our review. Included studies report experience diagnosis treatment emphysema; case non-English or non-Spanish excluded.
منابع مشابه
Bronchoscopic lung volume reduction
Surgical lung volume reduction can improve exercise performance and forced expiratory volume in one second in patients with emphysema. However, the procedure is associated with a 5% mortality rate and a nonresponse rate of ,25%. Accordingly, interest has focused on alternative ways of reducing lung volume. Two principle approaches are used: collapse of the diseased area using blockers placed en...
متن کاملBronchoscopic Lung Volume Reduction
The application of lung volume reduction surgery in clinical practice is limited by high postoperative morbidity and stringent selection criteria. This has been the impetus for the development of bronchoscopic approaches to lung volume reduction. A range of different techniques such as endobronchial blockers, airway bypass, endobronchial valves, thermal vapor ablation, biological sealants, and ...
متن کاملBronchoscopic lung volume reduction using tissue engineering principles.
Bronchoscopic lung volume reduction (BLVR), a minimally invasive procedure based on tissue engineering principles, was performed in six sheep with papain-induced experimental emphysema (EMPH). Physiologic measurements, at baseline, after generation of EMPH, and at 3 and 9 weeks after BLVR, included lung volumes, diffusing capacity (DL(CO)), pressure-volume relationships for the lung and chest w...
متن کاملCurrent status of bronchoscopic lung volume reduction with endobronchial valves.
INTRODUCTION Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Emphysema is a component of COPD characterised by hyperinflation resulting in reduced gas exchange and interference with breathing mechanics. Endoscopic lung volume reduction using one-way valves to induce atelectasis of the hyperinflated lobe has been developed and studied in clinic...
متن کاملEfficacy of bronchoscopic lung volume reduction: a meta-analysis
BACKGROUND Over the last several years, the morbidity, mortality, and high costs associated with lung volume reduction (LVR) surgery has fuelled the development of different methods for bronchoscopic LVR (BLVR) in patients with emphysema. In this meta-analysis, we sought to study and compare the efficacy of most of these methods. METHODS ELIGIBLE STUDIES WERE RETRIEVED FROM PUBMED AND EMBASE ...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2021
ISSN: ['1942-5546', '0025-6196']
DOI: https://doi.org/10.1016/j.mayocp.2020.03.027